PF-NP-200 Programmable Controlled-Rate Freezer

Liquid Nitrogen-Free Solution for GMP-Compliant Cell Cryopreservation
- The PF-NP-200 is a next-generation controlled-rate freezer designed specifically for advanced cell therapy and clinical applications. By eliminating the need for liquid nitrogen (LN2), it ensures a safe, contamination-free environment while delivering highly reproducible freezing for your most valuable cells.

APPLICATIONS
Cell Freezing
- Immune cells, stem cells, and more
Ideal for PBMCs, T-cells, iPS/ES cells, and other critical cell therapy samples.
- Sperm, embryos, tissues, and more
Applicable to a wide range of species, including human, bovine, equine, murine, avian, and fish species.
PRODUCT DESCRIPTION
Key Advantages (Why Choose PF-NP-200?)
100% Liquid Nitrogen-Free

Completely cryogen-free and alcohol-free operation. Eliminate the physical hazards, handling costs, and maintenance associated with traditional LN2 freezers.
Mnimized Contamination Risk

By removing liquid nitrogen from the freezing process, the PF-NP-200 reduces the risk of sample contamination, greatly enhancing the safety of clinical-grade cells.
GMP-Compliant & CPC-Ready

FDA 21 CFR Part 11 compliant (optional). Its clean and cryogen-free operation makes it the perfect fit for Cell Processing Centers (CPCs) and cleanroom environments.
High Reproducibility & Uniformity

Temperature control and monitoring ensure a precise and uniform freezing profile in every cycle. Achieve consistent, variation-free cell cryopreservation with maximum cell viability.
Space-Saving & Portable Design

Featuring a lightweight, space-saving design and a convenient built-in handle, the unit can be effortlessly moved and relocated by a single person.
Cooling Profiles
The PF-NP-200 ensures consistent, operator-independent results. Its temperature monitoring function records both sample and freezing block temperatures.

The graphs above demonstrate that the freezing rates of the cryovials and cell culture bags closely follow the block’s temperature changes (i.e., the preset temperature profiles). Even when two cell culture bags were stacked, the freezing profiles for both the top and bottom bags were nearly identical.
Freezing Block Choices

| Catalog Number | Description |
| PF-NP-200 | Programmable Controlled-Rate Freezer |
| PF-NP-C2X73 | Programmable Controlled-Rate Freezer |
| PF-NP-S0.25X20 | Programmable Controlled-Rate Freezer |
| PF-NP-S0.5X14 | Programmable Controlled-Rate Freezer |
| PF-NP-B25X2 | Programmable Controlled-Rate Freezer |
Specifications
- Intuitive touchscreen interface—no external PC required.
- Temperature logs easily exportable via USB.
- Built-in block heater for rapid temperature reset and consecutive cycles.
- Retains freezing programs during power outages.
- Optional car adapter enables operation via a 12V cigarette lighter socket.
| Temperature setting range | -80℃ ~ room temperature *Freezing block heating function is available. |
| Freezing rate | -0.1℃/min ~ -3℃/min (For some freezing blocks, the maximum rate is -1℃/min), PDI control |
| Refrigeration unit | Stirling cooler *Liquid nitrogen free |
| Freezing block | For cryovials (55X 2 ml vial) For cell culture bags (2X NIPRO F-050) |
| Temperature Setting and Display | Touchscreen for setting the cooling profile and temperature monitoring Log data can be exported as csv. files |
| Synchronization | Up to 8 units |
| Accessories | Temperature sensors and AC adaptor |
| Input Rating | AC100-240V, 50/60Hz |
| Electricity Consumption | Below 200W |
| Dimensions and Weight | 340(W) X 366(D) X 466(H) mm, 18 kg |
*All features and specifications subject to change without notice.
Note: The specifications and appearance of products on this page are subject to change without notice.




























