Transfection into Mouse/Rat Lung/Spleen/Liver/Kidney/Stomach/Intestine by Electroporation

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Transfection into Mouse/Rat Lung/Spleen/Liver/Kidney/Stomach/Intestine by Electroporation

APPLICATIONS

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PUBLICATIONS

  • Stomach

Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

Leibold J, Tsanov KM, Amor C, Ho YJ, Sánchez-Rivera FJ, Feucht J, Baslan T, Chen HA, Tian S, Simon J, Wuest A, Wilkinson JE, Lowe SW.

Nat Cancer. 2024 Feb;5(2):315-329.

  • Liver

EP4 receptor-associated protein (EPRAP) regulates gluconeogenesis in the liver and is associated with hyperglycemia in diabetic mice

Higuchi S, Fujikawa R, Nakatsuji M, Yasui M, Ikedo T, Nagata M, Mishima K, Irie K, Matsumoto M, Yokode M, Minami M

Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E410-E417.

  • Liver

Necroptosis microenvironment directs lineage commitment in liver cancer.

Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L.

Nature. 2018 Oct;562(7725):69-75.

  • Lung

Stable Somatic Gene Expression in Mouse Lungs Following Electroporation-mediated Tol2 Transposon Delivery.

Muliawan HS, Nakayama K, Yagi K, Ikeda K, Yagita K, Hirata K, Emoto N

Kobe J Med Sci. 2015 Oct 7;61(2):E47-53.

  • Liver

Adjuvant gemcitabine therapy improves survival in a locally induced, R0-resectable model of metastatic intrahepatic cholangiocarcinoma

Gürlevik E, Fleischmann-Mundt B, Armbrecht N, Longerich T, Woller N, Kloos A, Hoffmann D, Schambach A, Wirth TC, Manns MP, Zender L, Kubicka S, Kühnel F.

Hepatology. 2013 Sep;58(3):1031-41.

  • Intestine

Estrogen-dependent regulation of sodium/hydrogen exchanger-3 (NHE3) expression via estrogen receptor β in proximal colon of pregnant mice

Choijookhuu N, Sato Y, Nishino T, Endo D, Hishikawa Y, Koji T.

Histochem Cell Biol. 2012 May;137(5):575-87.

  • Spleen

Inhibition of nuclear delivery of plasmid DNA and transcription by interferon γ: hurdles to be overcome for sustained gene therapy.

Zang L, Nishikawa M, Machida K, Ando M, Takahashi Y, Watanabe Y, Takakura Y.

Gene Ther. 2011 Sep;18(9):891-7.

  • Liver

Reduction of fibrosis in a rat model of non-alcoholic steatohepatitis cirrhosis by human HGF gene transfection using electroporation.

Kiyama S, Yamada T, Iwata H, Sekino T, Matsuo H, Yoshida N, Miyahara T, Umeda Y, Matsuno Y, Kimura M, Matsumoto K, Nakamura T, Takemura H.

J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e471-6.

  • Liver

Deubiquitylation of histone H2A activates transcriptiona initiation via trans-histone cross-talk with H3K4 di- and trimethylation

Nakagawa T, Kajitani T, Togo S, Masuko N, Ohdan H, Hishikawa Y, Koji T, Matsuyama T, Ikura T, Muramatsu M, Ito T.

Genes Dev . 2008 Jan 1;22(1):37-49.

  • Liver

Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses.

Kawano T, Yamagata M, Takahashi H, Niidome Y, Yamada S, Katayama Y, Niidome T.

J Control Release. 2006 Apr 10;111(3):382-9.

  • Kidney

Local actions of endogenous angiotensin II in injured glomeruli

Ma J, Matsusaka T, Yang H, Kawachi H, Shimizu F, Isaka Y, Imai E, Kon V, Ichikawa I.

J Am Soc Nephrol. 2004 May;15(5):1268-76.

  • Kidney

Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats

Yazawa K, Isaka Y, Takahara S, Imai E, Ichimaru N, Shi Y, Namba Y, Okuyama A.

Nephrol Dial Transplant. 2004 Apr;19(4):812-6.

Electroporation

Drug Delivery and Transfection

Electro Cell Fusion

Fluorescence Quenching / in situ Hybridization Chain Reaction

Single-Cell/Micro-Particle Transfer

Cell Freezing

Mechanical Vibration