TiYO™
Autofluorescence Quenching Illuminator
- Efficient quenching with one simple step
- Photo-bleached LEDs for improved signal-to-noise ratio
- Effective for highly autofluorescent species
APPLICATIONS
Fluorescent Staining
- Mammalian Tissue Sections
- Human retina
- Mouse brain/heart/liver/kidney/spleen/intestine/skin/oviduct/submandibular gland/adrenal gland/bone marrow/testis/embryo
- Goat hypothalamus
- Fish Tissue Sections
- Chum salmon gills
- Banded houndshark gills/epigonal organ/pancreas/spleen/liver
- Zebrafish brain
- Amphibia tissue sections
- Axolotl limbs
- Avian Tissue Sections
- Chicken limbs
- Plant tissue sections
- Tomato stem
PRODUCT DESCRIPTION
Eliminating autofluorescence reveals even weak signals
Autofluorescence, a cause of background noise for microscopy, is derived from lipofuscin, elastin fibers, vitamin A, and other naturally occurring molecules, and can often make fluorescence imaging of tissues difficult.
The TiYO™ quenches this autofluorescence by the use of photo-bleaching LEDs to increase the signal-to-noise ratio.
- Just insert the sample and start. – No complicated procedures or special reagents required
- High power LEDs and optimized exposure complete quenching in 30 minutes to a few hours
Only autofluorescence is quenched!
Unlike conventional quenching reagents, only autofluorescence signal is affected.
There is no reduction in the fluorescence from stains.
Evaporative cooling system
Powerful light irradiation combined with effective cooling prevents samples from overheating during photobleaching procedure.
Specifications
| Control | Only power on/off *no other buttons/switches |
| Operation environment | 0 ~ +40°C、20 ~ 85%RH |
| Power Source | AC 100 ~ 240 V, 50/60 Hz |
| Max. power consumption | 310W |
| Size | 291 (W) × 210 (D) × 285 (H) mm |
| Weight | 10 kg |
| No. of samples per run | Up to 12 (microscope slides or TiYO™ chambers for free-floating sections/whole mount samples) |
TiYO™ was jointly developed and commercialized using the technology invented by Associate Professor Yosuke Tsuneoka, Faculty of Medicine, Toho University (patent pending: JP-A 2021-008882).
Note: The specifications and appearance of products on this page are subject to change without notice.