TiYO™ Autofluorescence Quenching Illuminator
Improve the signal-to-noise ratio in fluorescent tissue staining.
- Achieves efficient quenching in a single step
- Enables multi-round staining
- Effective for highly autofluorescent species
APPLICATIONS
Fluorescent Staining
PRODUCT DESCRIPTION
Eliminating autofluorescence reveals even weak signals
Autofluorescence, a cause of background noise for microscopy, is derived from lipofuscin, elastin fibers, vitamin A, and other naturally occurring molecules, and can often make fluorescence imaging of tissues difficult.
The TiYO™ Autofluorescence Quenching Illuminator reduces autofluorescence using photo-bleaching LEDs, thereby increasing the signal-to-noise ratio.
- Insert the sample and start—no complicated procedures or special reagents required
- High power LEDs and optimized exposure complete quenching in 30 minutes to a few hours
Only autofluorescence is quenched!
Unlike conventional quenching reagents, only autofluorescence signal is affected.
There is no reduction in the fluorescence from stains.
Evaporative cooling system
Powerful light irradiation combined with effective cooling prevents samples from overheating during photobleaching procedure.
Specifications
| Control | Only power on/off *no other buttons/switches |
| Operation environment | 0 ~ +40°C、20 ~ 85%RH |
| Power Source | AC 100 ~ 240 V, 50/60 Hz |
| Max. power consumption | 310W |
| Size | 291 (W) × 210 (D) × 285 (H) mm |
| Weight | 10 kg |
| No. of samples per run | Up to 12 (microscope slides or TiYO™ chambers for free-floating sections/whole mount samples) |
TiYO™ was jointly developed and commercialized using the technology invented by Associate Professor Yosuke Tsuneoka, Faculty of Medicine, Toho University (patent pending: JP-A 2021-008882).
FAQs -Frequently Asked Questions
RELATED PRODUCTS
TiYO-TRAY: Tray for microscope slides
TiYO-AD-WM: Chambers for floating or whole-mount samples (Pack of 6)
Note: The specifications and appearance of products on this page are subject to change without notice.