筋肉・皮膚・関節・軟骨・腫瘍・その他へのエレクトロポレーションによる遺伝子導入

筋肉

Identification of neutralizing epitopes in the preS2 domain of the hepatitis B virus

Keigo Yato, Mami Matsuda, Kento Fukano, Tomohisa Tanaka, Kohji Moriishi, Hironori Nishitsuji, Kunitada Shimotohno, Koji Tamura, Takaji Wakita, Masamichi Muramatsu, Takanobu Kato, Ryosuke Suzuki

Virus Res. 2023 Jan 2;323:199014.

筋肉

Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites

Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira

Int J Biol Sci. 2022 Jan 1;18(1):15-29.

筋肉

Enhanced Immune Responses and Protective Immunity to Zika Virus Induced by a DNA Vaccine Encoding a Chimeric NS1 Fused With Type 1 Herpes Virus gD Protein

Lennon Ramos Pereira, Rúbens Prince dos Santos Alves, Natiely Silva Sales, Robert Andreata-Santos, Aléxia Adrianne Venceslau-Carvalho, Samuel Santos Pereira, Maria Fernanda Castro-Amarante1, Mônica Josiane Rodrigues-Jesus, Marianna Teixeira de Pinho Favaro, Rosa Maria Chura-Chambi, Ligia Morganti and Luís Carlos de Souza Ferreira

Front. Med. Technol., 03 December 2020

筋肉

Gene Expression Profile at the Motor Endplate of the Neuromuscular Junction of Fast-Twitch Muscle

Kun Huang, Jin Li, Mikako Ito, Jun-Ichi Takeda, Bisei Ohkawara, Tomoo Ogi, Akio Masuda, Kinji Ohno

Front Mol Neurosci. 2020 Sep 8;13:154.

筋肉

Myopalladin Promotes Muscle Growth Through Modulation of the Serum Response Factor Pathway

Maria Carmela Filomena, Daniel L Yamamoto, Marco Caremani, Vinay K Kadarla, Giuseppina Mastrototaro, Simone Serio, Anupama Vydyanath, Margherita Mutarelli, Arcamaria Garofalo, Irene Pertici, Ralph Knöll, Vincenzo Nigro, Pradeep K Luther, Richard L Lieber, Moriah R Beck, Marco Linari, Marie-Louise Bang

J Cachexia Sarcopenia Muscle, 11 (1), 169-194 Feb 2020

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Keratinocyte Growth Factor (KGF) Induces Stem/Progenitor Cell Growth in Middle Ear Mucosa

Tomomi Yamamoto-Fukuda, Naotaro Akiyama, Hiromi Kojima

Int J Pediatr Otorhinolaryngol, 128, 109699 Jan 2020

筋肉

Bioavailability Study of Recombinant Plasmid DNA Nerve Growth Factor after Intramuscular Injection by Electroporation

V. V. Shilov, M. A. Yudin, N. G. Vengerovich, T. V. Shcherbakov, A. S. Bogacheva

МЕДИЦИНА, Т. 14. Вып. 2, pp. 89–97 14 Nov 2019

筋肉

Fibroblast Growth Factor 21 Controls Mitophagy and Muscle Mass

Lynette J Oost, Monika Kustermann, Andrea Armani, Bert Blaauw, Vanina Romanello

J Cachexia Sarcopenia Muscle, 10 (3), 630-642 Jun 2019

腫瘍

Upregulation of Transforming Growth Factor-Beta Type I Receptor by Interferon Consensus Sequence-Binding Protein in Osteosarcoma Cells

Jee Young Sung, Kyungsil Yoon, Sang-Kyu Ye, Sung-Ho Goh, Seog-Yun Park, June Hyuk Kim, Hyun Guy Kang, Yong-Nyun Kim, Byung-Kiu Park

Biochim Biophys Acta Mol Cell Res, 1866 (5), 761-772 May 2019

筋肉

Expression of a Soluble IL-10 Receptor Enhances the Therapeutic Effects of a Papillomavirus-Associated Antitumor Vaccine in a Murine Model

Jamile R Silva, Natiely S Sales, Mariângela O Silva, Luana R M M Aps, Ana C R Moreno, Elaine G Rodrigues, Luís C S Ferreira, Mariana O Diniz

Cancer Immunol Immunother, 68 (5), 753-763 May 2019

筋肉

Key Amino Acid Substitution for Infection-Enhancing Activity-Free Designer Dengue Vaccines

Atsushi Yamanaka, Eiji Konishi

iScience. 2019 Mar 29;13:125-137.

筋肉

Identification of CD4 and H-2K d-restricted Cytotoxic T Lymphocyte Epitopes on the Human Herpesvirus 6B Glycoprotein Q1 Protein

Satoshi Nagamata, Taiki Aoshi, Akiko Kawabata, Yoshiaki Yamagishi, Mitsuhiro Nishimura, Soichiro Kuwabara, Kouki Murakami, Hideto Yamada, Yasuko Mori

Sci Rep, 9 (1), 3911 2019 Mar 7

腫瘍

C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle

Ji Hae Lee, Jee Young Sung, Eun Kyung Choi, Hyun-Kyoung Yoon, Bo Ram Kang, Eun Kyung Hong, Byung-Kiu Park, Yong-Nyun Kim, Seung Bae Rho, Kyungsil Yoon

Cells, 8 (2) 2019 Feb 11

筋肉

Involvement of the Protein Kinase Akt2 in Insulin-Stimulated Rac1 Activation Leading to Glucose Uptake in Mouse Skeletal Muscle

Nobuyuki Takenaka, Natsumi Araki, Takaya Satoh

PLoS One, 14 (2), e0212219 2019 Feb 8 eCollection 2019

筋肉

Dendritic Cell Targeting Using a DNA Vaccine Induces Specific Antibodies and CD4 + T Cells to the Dengue Virus Envelope Protein Domain III

Arthur Baruel Zaneti, Marcio Massao Yamamoto, Fernando Bandeira Sulczewski, Bianca da Silva Almeida, Higo Fernando Santos Souza, Natália Soares Ferreira, Denicar Lina Nascimento Fabris Maeda, Natiely Silva Sales, Daniela Santoro Rosa, Luís Carlos de Souza Ferreira, Silvia Beatriz Boscardin

Front Immunol, 10, 59 2019 Jan 29 eCollection 2019

筋肉

IGFN1_v1 Is Required for Myoblast Fusion and Differentiation

Xiang Li, Jane Baker, Tobias Cracknell, Andrew R Haynes, Gonzalo Blanco

PLoS One, 12 (6), e0180217 2017 Jun 30 eCollection 2017

筋肉

Expression of Enhancing-Activity-Free Neutralizing Antibody Against Dengue Type 1 Virus in Plasmid-Inoculated Mice

Atsushi Yamanaka, Pannamthip Pitaksajjakul, Pongrama Ramasoota, Eiji Konishi

Vaccine, 33 (45), 6070-7 2015 Nov 9

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In Vivo Over-Expression of KGF Mimic Human Middle Ear Cholesteatoma

Tomomi Yamamoto-Fukuda, Naotaro Akiyama, Yasuaki Shibata, Haruo Takahashi, Tohru Ikeda, Takehiko Koji

Eur Arch Otorhinolaryngol, 272 (10), 2689-96 Oct 2015

皮膚

Electroporation-mediated intradermal delivery of DNA vaccines in nonhuman primates.

Adam L, Le Grand R, Martinon F.

Methods Mol Biol. 2014;1121:309-13.

腫瘍

Electroporation-mediated siRNA delivery into tumors.

Takei Y

Methods Mol Biol. 2014;1121:131-8.

筋肉

Novel polyvalent live vaccine against varicella-zoster and mumps virus infections.

Matsuura M et al.

Microbiol Immunol. 2013 Oct;57(10):704-14.

腫瘍

The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model.

Shibata MA et al.

BMC Med. 2010 Nov 3;8:69.

マウスかラットの皮膚

Injection site-dependent induction of immune response by DNA vaccine: comparison of skin and spleen as a target for vaccination.

Guan X et al.

The Journal of Gene Medicine, Volume 12, Issue 3, Pages 301-309, March 2010

腫瘍

Visualization of in vivo electroporation-mediated transgene expression in experimental tumors by optical and magnetic resonance imaging.

Aung W et al.

Gene Ther. 2009 Jul;16(7):830-9.

腫瘍

Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model.

Shibata MA et al.

Cancer Gene Ther. 2008 Dec;15(12):776-86.

腫瘍

Effective delivery of DNA into tumor cells and tissues by electroporation of polymer-DNA complex

Kang JH

Cancer Lett . 2008 Jul 8;265(2):281-8.

腫瘍

In vivo silencing of a molecular target by short interfering RNA electroporation: tumor vascularization correlates to delivery efficiency

Takei Y et al.

Mol Cancer Ther . 2008 Jan;7(1):211-21.

マウスかラットの皮膚

Modulation of scratching behavior by silencing an endogenou cyclooxygenase-1 gene in the skin through the administration of siRNA

Inoue et al.

J Gene Med . 2007 Nov;9(11):994-1001.

関節

Sonoporation mediated transduction of pDNA/siRNA into joint synovium in vivo

Saito et al.

J Orthop Res . 2007 Oct;25(10):1308-16.

筋肉

Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa

Saha S, Takeshita F, Sasaki S, Matsuda T, Tanaka T, Tozuka M, Takase K, Matsumoto T, Okuda K, Ishii N, Yamaguchi K, Klinman DM, Xin KQ, Okuda K.

Vaccine. 2006 Sep 11;24(37-39):6240-9.

筋肉

Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression.

Kawai M, Bessho K, Maruyama H, Miyazaki J, Yamamoto T

BMC Musculoskelet Disord. 2006 Aug 3;7:62.

筋肉

Toll-Like Receptor Adaptor Molecules Enhance DNA-Raised Adaptive Immune Responses against Influenza and Tumors through Activation of Innate Immunity

Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasaki S.

J Virol. 2006 Jul;80(13):6218-24.

筋肉

Immune deficiency enhances expression of recombinant human antibody in mice after nonviral in vivo gene transfer

Kitaguchi et al.

International Journal of Molecular Medicine, Volume 16, Number 4, Pages 683-688, October 2005

Production of research-grade antibody by in vivo electroporation of DNA-encoding target protein

Okahara F, Itoh K, Ebihara M, Kobayashi M, Maruyama H, Kanaho Y, Maehama T.

Anal Biochem. 2005 Jan 1;336(1):138-40.

関節

Electro-transfer of small interfering RNA ameliorated arthritis in rats

Inoue et al.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):903-8.

マウスかラットの皮膚

Epidermis-Targeted Gene Transfer Using In Vivo Electroporation

Maruyama et al.

Methods Mol Biol. 2005;289:431-6.

筋肉

Skeletal muscle targeting in vivo electroporation-mediated HGF gene therapy of bleomycin-induced pulmonary fibrosis in mice

Umeda Y, Marui T, Matsuno Y, Shirahashi K, Iwata H, Takagi H, Matsumoto K, Nakamura T, Kosugi A, Mori Y, Takemura H.

Lab Invest. 2004 Jul;84(7):836-44.

筋肉

Gene Therapy for Central Diabetes Insipidus: Effective Antidiuresis by Muscle-Targeted Gene Transfer

Yoshida M, Iwasaki Y, Asai M, Nigawara T, Oiso Y.

Endocrinology. 2004 Jan;145(1):261-8.

軟骨

Efficient gene delivery to articular cartilage using electroporation

Katayama et al.

Mod Rheumatol. 2003 Sep;13(3):243-9.

筋肉

Ectopic Bone Formation by Human Bone Morphogenetic Protein-2 Gene Transfer to Skeletal Muscle Using Transcutaneous Electroporation

Kawai M, Bessho K, Kaihara S, Sonobe J, Oda K, Iizuka T, Maruyama H.

Hum Gene Ther. 2003 Nov 1;14(16):1547-56.

筋肉

Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy

Xue F, Takahara T, Yata Y, Kuwabara Y, Shinno E, Nonome K, Minemura M, Takahara S, Li X, Yamato E, Watanabe A.

Gut. 2003 May;52(5):694-700.

筋肉

Anti-monocyte chemoattractant protein-1 gene therapy limits progression and destabilization of established atherosclerosis in apolipoprotein E-knockout mice

Inoue S, Egashira K, Ni W, Kitamoto S, Usui M, Otani K, Ishibashi M, Hiasa K, Nishida K, Takeshita A.

Circulation. 2002 Nov 19;106(21):2700-6.

筋肉

Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats

Ikeda et al.

Am J Physiol Heart Circ Physio . 2002 Nov;283(5):H2021-8.

関節

Successful genetic transduction in vivo into synovium by means of electroporation

Ohashi et al.

Biochem Biophys Res Commun. 2002 May 24;293(5):1530-5.

筋肉

Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation

Xue F, Takahara T, Yata Y, Minemura M, Morioka CY, Takahara S, Yamato E, Dono K, Watanabe A.

Gut. 2002 Apr;50(4):558-62.

筋肉

Gene Therapy for Mitochondrial Disease by Delivering Restriction Endonuclease SmaI into Mitochondria

Tanaka M, Borgeld HJ, Zhang J, Muramatsu S, Gong JS, Yoneda M, Maruyama W, Naoi M, Ibi T, Sahashi K, Shamoto M, Fuku N, Kurata M, Yamada Y, Nishizawa K, Akao Y, Ohishi N, Miyabayashi S, Umemoto H, Muramatsu T, Furukawa K, Kikuchi A, Nakano I, Ozawa K, Yagi K.

J Biomed Sci. 2002;9(6 Pt 1):534-41.

筋肉

Elevated gastrin secretion by in vivo gene electroporation in skeletal muscle

Yasui et al.

International Journal of Molecular Medicine, Volume 8, Number 5, Pages 489-494, November 2001

筋肉

Protection Against Autoimmune Myocarditis by Gene Transfer of Interleukin-10 by Electroporation

Watanabe et al.

Circulation . 2001 Sep 4;104(10):1098-100.

筋肉

Infectivity-Enhancing Antibodies to Ebola Virus Glycoprotein

Takada A, Watanabe S, Okazaki K, Kida H, Kawaoka Y.

J Virol. 2001 Mar;75(5):2324-30.